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Cat No. : KO884817-1
Gene Name: NDRG1
Gene No.: 10397
NM.: NM_001135242.1
KO Cell Line: HEK293
Genome Location: Chromosome 8 133284280(deletion) 133284283-133284309(deletion) 133284281(mutation)
Specification: 10E6cell/tube,2 tubes
Price: $4995
Turnaround Time: 2weeks
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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